I'm a lefty, so apparently that is why I'm weird. Being a lefty isn't that much different, except if you play little league and your best 2 positions are 2nd base and catcher (at the time only Mizuno stocked lefty catcher's mitts). I friggen HATED those desks that the chair was attached and binder-style notebooks*, spirals didn't seem to be a problem. Scissors can be a pain but I'll live. Having said all that, when things are made/sold specifically for lefty's, they usually don't warrant that much of an actual benefit (maybe thats why Ned's store failed).
Oh great, my lifespan is going to be shortened because scissors are harder to use.